Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

Alzheimer's Disease (AD) is the most common form of dementia and to date there is no cure or efficient prophylaxis. The cognitive decline correlates with the accumulation of amyloid-β (Aβ) in the walls of capillaries and arteries. Our group has demonstrated that interstitial fluid and Aβ are el...

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Bibliographic Details
Main Authors: Alexandra K. Diem, Matthew MacGregor Sharp, Maureen Gatherer, Neil W. Bressloff, Roxana O. Carare, Giles Richardson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer's disease
cerebral blood flow
perivascular drainage
intramural periarterial drainage
cerebral lymphatics
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00475/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00475/full

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