Keap1âNrf2 pathway: A promising target towards lung cancer prevention and therapeutics

Objectives: Drugs for targeted therapy have become a new strategy of adjuvant therapy for treatment of lung cancer. The Keap1 (kelch-like ECH-associated protein 1)âNrf2 (nuclear factor erythroid 2-related factor 2) pathway is recognized to be critical in regulating genes related to the cellular prot...

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Bibliographic Details
Main Authors: Ying-Hui Tong, Bo Zhang, Yun Fan, Neng-Ming Lin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2015-09-01
Series:Chronic Diseases and Translational Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X15000535