DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN

Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug. Baclofen was chosen because of its poor water solubility and short elimination half-life. Poloxamer 188 and PEG 6000 were used as solid disp...

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Bibliographic Details
Main Authors: K. H. Janardhana, R. Deveswaran, S. Bharath, B.V. Basavaraj, V. Madhavan
Format: Article
Language:English
Published: El Oued University 2013-12-01
Series:Journal of Fundamental and Applied Sciences
Online Access:http://old.jfas.info/index.php/JFAS/article/view/234-460/pdf