DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN
Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug. Baclofen was chosen because of its poor water solubility and short elimination half-life. Poloxamer 188 and PEG 6000 were used as solid disp...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
El Oued University
2013-12-01
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Series: | Journal of Fundamental and Applied Sciences |
Online Access: | http://old.jfas.info/index.php/JFAS/article/view/234-460/pdf |