METROID: an automated method for robust quantification of subcellular fluorescence events at low SNR

Abstract Background In cell biology, increasing focus has been directed to fast events at subcellular space with the advent of fluorescent probes. As an example, voltage sensitive dyes (VSD) have been used to measure membrane potentials. Yet, even the most recently developed genetically encoded volt...

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Bibliographic Details
Main Authors: Marcelo Zoccoler, Pedro X. de Oliveira
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03661-9