Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish.

Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish.

Zic3 regulates early embryonic patterning in vertebrates. Loss of Zic3 function is known to disrupt gastrulation, left-right patterning, and neurogenesis. However, molecular events downstream of this transcription factor are poorly characterized. Here we use the zebrafish as a model to study the dev...

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Bibliographic Details
Main Authors: Cecilia L Winata, Igor Kondrychyn, Vibhor Kumar, Kandhadayar G Srinivasan, Yuriy Orlov, Ashwini Ravishankar, Shyam Prabhakar, Lawrence W Stanton, Vladimir Korzh, Sinnakaruppan Mathavan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3814314?pdf=render

Internet

http://europepmc.org/articles/PMC3814314?pdf=render

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