Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice

Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice

Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis. Although age-related alterations in immune responses are known, it remains unclear whether aging modulates the antibody p...

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Bibliographic Details
Main Authors: Yumiko Ichihara, Mitsuhiro Okano, Keiko Nishioka, Noriko Manabe, Naoto Ichihara, Fumihiko Jitsunari, Tazuko Fujiwara, Kazunori Nishizaki
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Allergology International
Subjects:
aged mouse
immunosuppression
phospholipase A2
restraint stress
specific antibody
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306705

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http://www.sciencedirect.com/science/article/pii/S1323893015306705

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