Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro

Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro

Abstract Human umbilical cord mesenchymal stem cells (huMSCs) can treat primary ovarian insufficiency (POI) related to ovarian granulosa cell (OGC) apoptosis caused by cisplatin chemotherapy. Exosomes are a class of membranous vesicles with diameters of 30–200 nm that are constitutively released by...

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Bibliographic Details
Main Authors: Liping Sun, Dong Li, Kun Song, Jianlu Wei, Shu Yao, Zhao Li, Xuantao Su, Xiuli Ju, Lan Chao, Xiaohui Deng, Beihua Kong, Li Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02786-x

Internet

https://doi.org/10.1038/s41598-017-02786-x

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