Modulated Electro-Hyperthermia Resolves Radioresistance of Panc1 Pancreas Adenocarcinoma and Promotes DNA Damage and Apoptosis In Vitro

Modulated Electro-Hyperthermia Resolves Radioresistance of Panc1 Pancreas Adenocarcinoma and Promotes DNA Damage and Apoptosis In Vitro

The poor outcome of pancreas ductal adenocarcinomas (PDAC) is frequently linked to therapy resistance. Modulated electro-hyperthermia (mEHT) generated by 13.56 MHz capacitive radiofrequency can induce direct tumor damage and promote chemo- and radiotherapy. Here, we tested the effect of mEHT either...

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Bibliographic Details
Main Authors: Gertrud Forika, Andrea Balogh, Tamas Vancsik, Attila Zalatnai, Gabor Petovari, Zoltan Benyo, Tibor Krenacs
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
modulated electro-hyperthermia (mEHT)
Panc1 pancreas adenocarcinoma
caspase-dependent apoptosis
p21<sup>waf1</sup> upregulation
resolution of radioresistance
Online Access:https://www.mdpi.com/1422-0067/21/14/5100

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https://www.mdpi.com/1422-0067/21/14/5100

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