Protective Effects of Ursodeoxycholic Acid on Valproic Acid Induced Hepatotoxicity in Epileptic Children with Recurrent Seizure; A Double-Blinded Randomized Clinical Trial

Protective Effects of Ursodeoxycholic Acid on Valproic Acid Induced Hepatotoxicity in Epileptic Children with Recurrent Seizure; A Double-Blinded Randomized Clinical Trial

Background: There are controversies regarding the protective role of ursodeoxycholic acid (UDCA) against valproic acid (VPA)-induced hepatotoxicity in children. In the present clinical trial, we assessed the potential role of UDCA in preventing VPA-induced fluctuations of hepatic enzymes in epilepti...

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Bibliographic Details
Main Authors: Iraj Shahramian, Ali Bazi, Rosa Mostafaee, Mohammad Hasan Mohammadi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-03-01
Series:Pharmaceutical Sciences
Subjects:
ursodeoxycholic acid
valproic acid
liver enzymes
hepatic toxicity
Online Access:https://ps.tbzmed.ac.ir/PDF/Pharm-32904

Internet

https://ps.tbzmed.ac.ir/PDF/Pharm-32904

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