Effect of oral magnesium sulfate administration on blood glucose hemostasis via inhibition of gluconeogenesis and FOXO1 gene expression in liver and muscle in diabetic rats

Effect of oral magnesium sulfate administration on blood glucose hemostasis via inhibition of gluconeogenesis and FOXO1 gene expression in liver and muscle in diabetic rats

The present study was designed to investigate the possible role of Mg2+ in suppression of phosphoenolpyruvate carboxy kinase (PEPCK) enzyme via inhibition of FOXO1gene expression in liver and we also examined whether Mg contributes to decrease blood glucose in muscle via inhibiting FOXO1 gene and pr...

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Bibliographic Details
Main Authors: Ayeshe Barooti, Mitra Kamran, Fatemeh Kharazmi, Ebrahim Eftakhar, Kianoosh Malekzadeh, Ardeshir Talebi, Nepton Soltani
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diabetes
Mg
FOXO1
PEPCK
Insulin
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221834277X

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http://www.sciencedirect.com/science/article/pii/S075333221834277X

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