Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy

Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy

Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal damage in preclinical reports. We genotyped 1088 diabetic kidney disease (DK...

Full description

Bibliographic Details
Main Authors: Sonia Mota-Zamorano, Nicolás R. Robles, Luz M. González, José M. Valdivielso, Juan Lopez-Gomez, Bárbara Cancho, Guadalupe García-Pino, Guillermo Gervasini
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Clinical Medicine
Subjects:
chronic kidney disease
diabetic kidney disease
diabetes mellitus
CYP4F2
Online Access:https://www.mdpi.com/2077-0383/10/17/3980

Internet

https://www.mdpi.com/2077-0383/10/17/3980

Similar Items