Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy
Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal damage in preclinical reports. We genotyped 1088 diabetic kidney disease (DK...
Main Authors: | Sonia Mota-Zamorano, Nicolás R. Robles, Luz M. González, José M. Valdivielso, Juan Lopez-Gomez, Bárbara Cancho, Guadalupe García-Pino, Guillermo Gervasini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/10/17/3980 |
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