Chronic high-fat feeding impairs adaptive induction of mitochondrial fatty acid combustion-associated proteins in brown adipose tissue of mice

Chronic high-fat feeding impairs adaptive induction of mitochondrial fatty acid combustion-associated proteins in brown adipose tissue of mice

Since brown adipose tissue (BAT) is involved in thermogenesis using fatty acids as a fuel, BAT activation is a potential strategy for treating obesity and diabetes. However, whether BAT fatty acid combusting capacity is preserved in these conditions has remained unclear. We therefore evaluated expre...

Full description

Bibliographic Details
Main Authors: Takayuki Ohtomo, Kanako Ino, Ryota Miyashita, Maya Chigira, Masahiko Nakamura, Koji Someya, Niro Inaba, Mariko Fujita, Mitsuhiro Takagi, Junji Yamada
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Acyl-CoA thioesterase
Brown adipose tissue
Fatty acid oxidation
Obesity
Uncoupling protein
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081730047X

Internet

http://www.sciencedirect.com/science/article/pii/S240558081730047X

Similar Items