Effect of <em>CYP3A4</em>*22 and <em>PPAR-α</em> Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention

Effect of <em>CYP3A4</em>*22 and <em>PPAR-α</em> Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutaneous Coronary Intervention

This study aims to determine whether genetic variants that influence <i>CYP3A4</i> expression are associated with platelet reactivity in clopidogrel-treated patients undergoing elective percutaneous coronary intervention (PCI), and to evaluate the influence of statin/fibrate co-medicatio...

Full description

Bibliographic Details
Main Authors: Thomas O. Bergmeijer, Alfi Yasmina, Gerrit J. A. Vos, Paul W. A. Janssen, Christian M. Hackeng, Johannes C. Kelder, Shefali S. Verma, Marylyn D. Ritchie, Li Gong, Teri E. Klein, ICPC investigators, Anthonius de Boer, Olaf H. Klungel, Jurriën M. ten Berg, Vera H. M. Deneer
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
clopidogrel
PPAR
statin
fibrate
CYP3A4
genotyping
Online Access:https://www.mdpi.com/2073-4425/11/9/1068

Internet

https://www.mdpi.com/2073-4425/11/9/1068

Similar Items