VAMP3 and SNAP23 as Potential Targets for Preventing the Disturbed Flow-Accelerated Thrombus Formation

VAMP3 and SNAP23 as Potential Targets for Preventing the Disturbed Flow-Accelerated Thrombus Formation

Disturbed blood flow has been recognized to promote platelet aggregation and thrombosis via increasing accumulation of von Willebrand factor (VWF) at the arterial post-stenotic sites. The mechanism underlying the disturbed-flow regulated endothelial VWF production remains elusive. Here we described...

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Bibliographic Details
Main Authors: Juan-Juan Zhu, Zhi-Tong Jiang, Chen Liu, Yi-Feng Xi, Jin Wang, Fang-Fang Yang, Wei-Juan Yao, Wei Pang, Li-Li Han, Yong-He Zhang, An-Qiang Sun, Jing Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
thrombosis
VAMP3
endothelial cells
disturbed flow
SNAP23
VWF
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.576826/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.576826/full

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