DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein

<p>Abstract</p> <p>Background</p> <p>C-Myc is a short-lived oncoprotein that is destroyed by ubiquitin-mediated proteolysis. Dysregulated accumulation of c-Myc commonly occurs in human cancers. Some of those cases with the dysregulated c-Myc protein accumulation are att...

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Bibliographic Details
Main Authors: Wang Yu, Shang Zeng-Fu, Huo Yan-Ying, Zhang Shi-Meng, Xu Qin-Zhi, Yang Dong-Yan, An Jing, Wu De-Chang, Zhou Ping-Kun
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/32