Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

Abstract Background SHOX2 and SEPT9 methylation in circulating cell-free DNA (ccfDNA) in blood are established powerful and clinically valuable biomarkers for diagnosis, staging, prognosis, and monitoring of cancer patients. The aim of the present study was to evaluate different quantification algor...

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Bibliographic Details
Main Authors: Luka de Vos, Heidrun Gevensleben, Andreas Schröck, Alina Franzen, Glen Kristiansen, Friedrich Bootz, Dimo Dietrich
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Clinical Epigenetics
Subjects:
Free-circulating cell-free DNA
DNA methylation
SHOX2
SEPT9
Diagnostic accuracy
Risk stratification
Online Access:http://link.springer.com/article/10.1186/s13148-017-0425-4

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http://link.springer.com/article/10.1186/s13148-017-0425-4

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