Prenatal sevoflurane exposure causes neuronal excitatory/inhibitory imbalance in the prefrontal cortex and neurofunctional abnormality in rats

Prenatal sevoflurane exposure causes neuronal excitatory/inhibitory imbalance in the prefrontal cortex and neurofunctional abnormality in rats

The balance of excitatory and inhibitory neurons in the central nervous system is critical for maintaining brain function and sevoflurane, a general anesthetic and an GABA receptor modulator, may change the balance of excitatory and inhibitory neurons in the cortex during early brain development. He...

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Bibliographic Details
Main Authors: Tianyun Zhao, Yanxin Chen, Zhixiang Sun, Ziwen Shi, Jingwen Qin, Junming Lu, Chuanxiang Li, Daqing Ma, Libing Zhou, Xingrong Song
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Neurobiology of Disease
Subjects:
Sevoflurane
Prenatal exposure
E/I balance
Interneuron
Depression
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612030396X

Internet

http://www.sciencedirect.com/science/article/pii/S096999612030396X

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