Salicylate Inhibits Thrombopoiesis in Rat Megakaryocytes by Changing the Membrane Micro-Architecture

Salicylate Inhibits Thrombopoiesis in Rat Megakaryocytes by Changing the Membrane Micro-Architecture

Background/Aims: Salicylate causes drug-induced immune thrombocytopenia. However, some clinical studies indicate the presence of additional mechanisms in the drug-induced thrombocytopenia, by which the platelet production from megakaryocytes may directly be affected. Since salicylate is amphiphilic...

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Bibliographic Details
Main Authors: Itsuro Kazama, Asuka Baba, Yasuhiro Endo, Hiroaki Toyama, Yutaka Ejima, Mitsunobu Matsubara, Masahiro Tachi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Salicylate
Megakaryocytes
Membrane capacitance
Thrombopoiesis
Membrane micro-architecture
Online Access:http://www.karger.com/Article/FullText/374039

Internet

http://www.karger.com/Article/FullText/374039

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