Obtaining, Evaluation, and Optimization of Doxycycline-Loaded Microparticles Intended for the Local Treatment of Infectious Arthritis

Obtaining, Evaluation, and Optimization of Doxycycline-Loaded Microparticles Intended for the Local Treatment of Infectious Arthritis

Compared to the classical systemic administration, the local drug release has some advantages, such as lack of systemic toxicity and associated side effects, increased patient compliance, and a low rate of bacterial resistance. Biopolymers are widely used to design sustained drug delivery systems an...

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Bibliographic Details
Main Authors: Maria Minodora Marin, Mădălina Georgiana Albu Kaya, Horia Iovu, Cristina Elena Stavarache, Ciprian Chelaru, Rodica Roxana Constantinescu, Cristina-Elena Dinu-Pîrvu, Mihaela Violeta Ghica
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Coatings
Subjects:
microcapsules
type II collagen
arthritis
doxycycline
Taguchi design
Online Access:https://www.mdpi.com/2079-6412/10/10/990

Internet

https://www.mdpi.com/2079-6412/10/10/990

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