An updated radiosynthesis of [18F]AV1451 for tau PET imaging

An updated radiosynthesis of [18F]AV1451 for tau PET imaging

Abstract Background [18F]AV1451 is a commonly used radiotracer for imaging tau deposits in Alzheimer’s disease (AD) and related non-AD tauopathies. Existing radiosyntheses of [18F]AV1451 require complex purifications to provide doses suitable for use in clinical imaging studies. To address this issu...

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Bibliographic Details
Main Authors: Andrew V. Mossine, Allen F. Brooks, Bradford D. Henderson, Brian G. Hockley, Kirk A. Frey, Peter J. H. Scott
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Tau imaging
Brain PET
[18F]T807
Flortaucipir F18
Fluorine-18 radiochemistry
Automated radiosynthesis
Online Access:http://link.springer.com/article/10.1186/s41181-017-0027-7

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http://link.springer.com/article/10.1186/s41181-017-0027-7

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