Human cytomegalovirus (HCMV)-specific CD4+ and CD8+ T cells are both required for prevention of HCMV disease in seropositive solid-organ transplant recipients.

In solid-organ transplant recipients (SOTR) the protective role of human cytomegalovirus (HCMV)-specific CD4+, CD8+ and γδ T-cells vs. HCMV reactivation requires better definition. The aim of this study was to investigate the relevant role of HCMV-specific CD4+, CD8+ and γδ T-cells in different clin...

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Bibliographic Details
Main Authors: Elisa Gabanti, Francesca Bruno, Daniele Lilleri, Chiara Fornara, Paola Zelini, Ilaria Cane, Clara Migotto, Eleonora Sarchi, Milena Furione, Giuseppe Gerna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25166270/?tool=EBI