Establishment of a Lung Cancer Discriminative Model Based on an Optimized Support Vector Machine Algorithm and Study of Key Targets of Wogonin in Lung Cancer

Establishment of a Lung Cancer Discriminative Model Based on an Optimized Support Vector Machine Algorithm and Study of Key Targets of Wogonin in Lung Cancer

An optimized support vector machine model was used to construct a lung cancer diagnosis model based on serological indicators, and a molecular regulation model of Wogonin, a component of Scutellaria baicalensis, was established. Serological indexes of patients were collected, the grid search method...

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Bibliographic Details
Main Authors: Lin Wang, Jianhua Zhang, Guoyong Shan, Junting Liang, Wenwen Jin, Yingyue Li, Fangchu Su, Yanhua Ba, Xifeng Tian, Xiaoyan Sun, Dayong Zhang, Weihua Zhang, Chuan liang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
lung cancer
wogonin
serum index
SVM
network pharmacology
key targets
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.728937/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.728937/full

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