Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes
<p>Abstract</p> <p>Background</p> <p>Human immunodeficiency virus type 1 (HIV-1)-based gene delivery systems are popular due to their superior efficiency of transduction of primary cells. However, these systems cannot be readily used for delivery of anti-HIV-1 genes tha...
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Format: | Article |
Language: | English |
Published: |
BMC
2008-06-01
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Series: | AIDS Research and Therapy |
Online Access: | http://www.aidsrestherapy.com/content/5/1/11 |