High Purity Isolation of Low Density Neutrophils Casts Doubt on Their Exceptionality in Health and Disease

Low density neutrophils (LDNs) are described in a number of inflammatory conditions, cancers and infections and associated with immunopathology, and a mechanistic role in disease. The role of LDNs at homeostasis in healthy individuals has not been investigated. We have developed an isolation protoco...

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Bibliographic Details
Main Authors: Gareth R. Hardisty, Frances Llanwarne, Danielle Minns, Jonathan L. Gillan, Donald J. Davidson, Emily Gwyer Findlay, Robert D. Gray
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.625922/full