Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

The use of small interference RNA (siRNA) to target oncogenes is a promising treatment approach for cancer. However, siRNA cancer therapies are hindered by poor delivery of siRNA to cancer cells. Transferrin receptor (TfR) is overexpressed in many types of tumor cells and therefore is a potential ta...

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Bibliographic Details
Main Authors: Yuran Xie, Bryan Killinger, Anna Moszczynska, Olivia M. Merkel
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
siRNA delivery
transferrin receptor
targeting
peptide
polyethylenimine
Online Access:http://www.mdpi.com/1420-3049/21/10/1334

Internet

http://www.mdpi.com/1420-3049/21/10/1334

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