Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature

Pulmonary arterial hypertension (PAH) is a life-threatening disease that is characterized by an increase in pulmonary vascular pressure, leading to ventricular failure and high morbidity and mortality. Resveratrol, a phenolic compound and a sirtuin 1 pathway activator, has known dietary benefits and...

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Main Authors: Eduardo Vázquez-Garza, Judith Bernal-Ramírez, Carlos Jerjes-Sánchez, Omar Lozano, Edgar Acuña-Morín, Mariana Vanoye-Tamez, Martín R. Ramos-González, Héctor Chapoy-Villanueva, Luis Pérez-Plata, Luis Sánchez-Trujillo, Guillermo Torre-Amione, Alicia Ramírez-Rivera, Gerardo García-Rivas
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/1841527