Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
Hasan and Berdichevsky report the use of 3D neuronal-astrocyte co-cultures in PDMS confinement to enable the study of aggregation, migration, contractility, and sorting of these cells. They show that aggregation is a neuron mediated process, and formation of astrocyte-rich sheaths in 3D cultures dep...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02104-2 |