Specificity in PDZ-peptide interaction networks: Computational analysis and review

Globular PDZ domains typically serve as protein–protein interaction modules that regulate a wide variety of cellular functions via recognition of short linear motifs (SLiMs). Often, PDZ mediated-interactions are essential components of macromolecular complexes, and disruption affects the entire scaf...

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Bibliographic Details
Main Authors: Jeanine F. Amacher, Lionel Brooks, 3rd, Thomas H. Hampton, Dean R. Madden
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Structural Biology: X
Subjects:
PDZ
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152420300040