Specificity in PDZ-peptide interaction networks: Computational analysis and review
Globular PDZ domains typically serve as protein–protein interaction modules that regulate a wide variety of cellular functions via recognition of short linear motifs (SLiMs). Often, PDZ mediated-interactions are essential components of macromolecular complexes, and disruption affects the entire scaf...
Main Authors: | Jeanine F. Amacher, Lionel Brooks, 3rd, Thomas H. Hampton, Dean R. Madden |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Journal of Structural Biology: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152420300040 |
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