Intravital imaging tumor screen used to identify novel metastasis-blocking therapeutic targets

Intravital imaging tumor screen used to identify novel metastasis-blocking therapeutic targets

Cancer cell motility is a key driver of metastasis. Although the intravasation of cancer cells into the blood stream is highly dependent on their motility and metastatic dissemination is the primary cause of cancer related deaths, current therapeutic strategies do not target the genes and proteins t...

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Bibliographic Details
Main Authors: Konstantin Stoletov, Lian Willetts, Perrin H. Beatty, John D. Lewis
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-10-01
Series:Cell Stress
Subjects:
ex ovo chick embryo model
fluorescence time-lapse intravital imaging
high throughput sequencing
intravasation
metastatic cancer
shRNA library
therapeutic targets
Online Access:http://www.cell-stress.com/researcharticles/intravital-imaging-tumor-screen-used-to-identify-novel-metastasis-blocking-therapeutic-targets/

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http://www.cell-stress.com/researcharticles/intravital-imaging-tumor-screen-used-to-identify-novel-metastasis-blocking-therapeutic-targets/

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