Isolation of Specific Genomic Regions and Identification of Their Associated Molecules by Engineered DNA-Binding Molecule-Mediated Chromatin Immunoprecipitation (enChIP) Using the CRISPR System and TAL Proteins

Isolation of Specific Genomic Regions and Identification of Their Associated Molecules by Engineered DNA-Binding Molecule-Mediated Chromatin Immunoprecipitation (enChIP) Using the CRISPR System and TAL Proteins

Comprehensive understanding of genome functions requires identification of molecules (proteins, RNAs, genomic regions, etc.) bound to specific genomic regions of interest in vivo. To perform biochemical and molecular biological analysis of specific genomic regions, we developed engineered DNA-bindin...

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Bibliographic Details
Main Authors: Hodaka Fujii, Toshitsugu Fujita
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:International Journal of Molecular Sciences
Subjects:
ChIP
chromatin immunoprecipitation
enChIP
engineered DNA-binding molecule-mediated ChIP
chromatin
epigenetics
genome function
CRISPR
TAL
Online Access:http://www.mdpi.com/1422-0067/16/9/21802

Internet

http://www.mdpi.com/1422-0067/16/9/21802

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