Effect of Thyrotropin on Osteopontin, Integrin αvβ3, and VCAM-1 in the Endothelium via Activation of Akt

Numerous epidemiological studies have shown that subclinical hypothyroidism (SCH) can impair endothelial function and cause dyslipidemia. Studies have evaluated the effects of thyroid stimulating hormone (TSH) on endothelial cells, but the mechanism underlying the proatherosclerotic effect of increa...

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Bibliographic Details
Main Authors: Yumeng Yan, Fengwei Jiang, Yaxin Lai, Haoyu Wang, Aihua Liu, Chuyuan Wang, Yuanyuan Zhang, Weiping Teng, Zhongyan Shan
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/9/1484