Neuroprotective effect of Betalain against AlCl3-induced Alzheimer's disease in Sprague Dawley Rats via putative modulation of oxidative stress and nuclear factor kappa B (NF-κB) signaling pathway

Neuroprotective effect of Betalain against AlCl3-induced Alzheimer's disease in Sprague Dawley Rats via putative modulation of oxidative stress and nuclear factor kappa B (NF-κB) signaling pathway

Alzheimer's disease (AD) is the most progressive form of neurodegenerative disease, which severely impairs cognitive function. Oxidative stress is identified to contribute to the mechanisms responsible for the pathogenesis of such neurodegenerative diseases. Aluminum is a potent neurotoxin for...

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Bibliographic Details
Main Authors: Di Shunan, Miao Yu, Huibo Guan, Yanyan Zhou
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer's disease (AD)
Dementia
Betalain
Oxidative stress
Inflammation
Aluminium chloride (AlCl3)
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001542

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http://www.sciencedirect.com/science/article/pii/S0753332221001542

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