Emerging Roles of N6-Methyladenosine on HIV-1 RNA Metabolism and Viral Replication

Emerging Roles of N6-Methyladenosine on HIV-1 RNA Metabolism and Viral Replication

N6-methyladenosine (m6A) is the most abundant internal modification present in Eukaryotic mRNA. The functions of this chemical modification are mediated by m6A-binding proteins (m6A readers) and regulated by methyltransferases (m6A writers) and demethylases (m6A erasers), which together are proposed...

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Bibliographic Details
Main Authors: Sebastián Riquelme-Barrios, Camila Pereira-Montecinos, Fernando Valiente-Echeverría, Ricardo Soto-Rifo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
N6-methyladenosine
HIV-1 genomic RNA
gene expression
Rev
YTHDF proteins
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00576/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00576/full

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