ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry.

Interferon stimulated genes (ISGs) target viruses at various stages of their infectious life cycles, including at the earliest stage of viral entry. Here we identify ArfGAP with dual pleckstrin homology (PH) domains 2 (ADAP2) as a gene upregulated by type I IFN treatment in a STAT1-dependent manner....

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Bibliographic Details
Main Authors: Qian Shu, Nicholas J Lennemann, Saumendra N Sarkar, Yoel Sadovsky, Carolyn B Coyne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4570769?pdf=render