Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer

Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer

Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma (PDAC) cases. No major causative gene defect has yet been identified, but germline mutations in predisposition genes <i>BRCA1/2</i>,...

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Bibliographic Details
Main Authors: Emily P. Slater, Lisa M. Wilke, Lutz Benedikt Böhm, Konstantin Strauch, Manuel Lutz, Norman Gercke, Elvira Matthäi, Kari Hemminki, Asta Försti, Matthias Schlesner, Nagarajan Paramasivam, Detlef K. Bartsch
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
familial pancreatic cancer
WGS
genetic variants
Online Access:https://www.mdpi.com/2075-4426/11/7/631

Internet

https://www.mdpi.com/2075-4426/11/7/631

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