Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function

New blood vessel sprouting (angiogenesis) and vascular physiology are fundamental features of metazoan species but we do not fully understand how signal transduction pathways regulate diverse vascular responses. The vascular endothelial growth factor (VEGF) family bind membrane-bound receptor tyrosi...

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Bibliographic Details
Main Authors: Gareth W. Fearnley, Izma Abdul-Zani, Antony M. Latham, Monica C. Hollstein, John E. Ladbury, Stephen B. Wheatcroft, Adam F. Odell, Sreenivasan Ponnambalam
Format: Article
Language:English
Published: The Company of Biologists 2019-05-01
Series:Biology Open
Subjects:
Endothelial
VEGF-A
Tpl2
Signal transduction
Angiogenesis
Online Access:http://bio.biologists.org/content/8/5/bio034215

Internet

http://bio.biologists.org/content/8/5/bio034215

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