Development of a model for fibroblast-led collective migration from breast cancer cell spheroids to study radiation effects on invasiveness

Development of a model for fibroblast-led collective migration from breast cancer cell spheroids to study radiation effects on invasiveness

Abstract Background Invasiveness is a major factor contributing to metastasis of tumour cells. Given the broad variety and plasticity of invasion mechanisms, assessing potential metastasis-promoting effects of irradiation for specific mechanisms is important for further understanding of potential ad...

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Main Authors: Jia Mei, Claudia Böhland, Anika Geiger, Iris Baur, Kristina Berner, Steffen Heuer, Xue Liu, Laura Mataite, M. Camila Melo-Narváez, Erdem Özkaya, Anna Rupp, Christian Siebenwirth, Felix Thoma, Matthias F. Kling, Anna A. Friedl
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Radiation Oncology
Online Access:https://doi.org/10.1186/s13014-021-01883-6

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https://doi.org/10.1186/s13014-021-01883-6

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