CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

Juvenile myelomonocytic leukemia (JMML), a rare myelodysplastic/myeloproliferative neoplasm of early childhood, is characterized by clonal growth of RAS signaling addicted stem cells. JMML subtypes are defined by specific RAS pathway mutations and display distinct gene, microRNA (miRNA) and long non...

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Bibliographic Details
Main Authors: Anna Dal Molin, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Jan Philippé, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Tim Lammens, Stefania Bortoluzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CircRNAs
regulatory networks
juvenile myelomonocytic leukemia
microRNAs
RNA-Seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.613540/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.613540/full

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