Optimization of a Luciferase-Expressing Non-Invasive Intrapleural Model of Malignant Mesothelioma in Immunocompetent Mice

Optimization of a Luciferase-Expressing Non-Invasive Intrapleural Model of Malignant Mesothelioma in Immunocompetent Mice

Malignant Pleural Mesothelioma (MPM) is an aggressive tumor of the pleural lining that is usually identified at advanced stages and resistant to current therapies. Appropriate pre-clinical mouse tumor models are of pivotal importance to study its biology. Usually, tumor cells have been injected intr...

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Bibliographic Details
Main Authors: Elisabeth Digifico, Marco Erreni, Federico Simone Colombo, Camilla Recordati, Roberta Migliore, Roberta Frapolli, Maurizio D’Incalci, Cristina Belgiovine, Paola Allavena
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
malignant pleural mesothelioma
MPM mouse model
in vivo imaging
intrathoracic injection
inflammation
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/12/8/2136

Internet

https://www.mdpi.com/2072-6694/12/8/2136

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