Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume

In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in pulmonary research because it provides longitudinal information on dynamic disease processes in a field in which ex vivo assessment of experimental disease models is still the gold standard. To optimize the quantitat...

Full description

Bibliographic Details
Main Authors: Greetje Vande Velde, Jennifer Poelmans, Ellen De Langhe, Amy Hillen, Jeroen Vanoirbeek, Uwe Himmelreich, Rik J. Lories
Format: Article
Language:English
Published: The Company of Biologists 2016-01-01
Series:Disease Models & Mechanisms
Subjects:
Quantification
Pulmonary fibrosis
Lung inflammation
Infectious diseases
Micro-computed tomography
In vivo
Lung volume
Disease models
Biomarkers
Bleomycin
Aspergillosis
Cryptococcosis
Online Access:http://dmm.biologists.org/content/9/1/91

Internet

http://dmm.biologists.org/content/9/1/91

Similar Items