Impact of serum high mobility group box 1 and soluble receptor for advanced glycation end-products on subclinical atherosclerosis in patients with granulomatosis with polyangiitis.

The objective of this study was to evaluate whether levels of high mobility group box 1 (HMGB1) in granulomatosis with polyangiitis (GPA) patients are associated with carotid atherosclerosis, related to levels of soluble receptor for advanced glycation end-products (sRAGE) and influenced by immunosu...

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Bibliographic Details
Main Authors: Alexandre W S de Souza, Karina de Leeuw, Mirjan M van Timmeren, Pieter C Limburg, Coen A Stegeman, Marc Bijl, Johanna Westra, Cees G M Kallenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4002481?pdf=render