The association between monocytic myeloid-derived suppressor cells levels and the anti-tumor efficacy of anti-PD-1 therapy in NSCLC patients

The association between monocytic myeloid-derived suppressor cells levels and the anti-tumor efficacy of anti-PD-1 therapy in NSCLC patients

Monocytic myeloid-derived suppressor cells (M-MDSCs), granulocytic MDSC (G-MDSCs) and regulatory T cells (Tregs) inhibit adaptive anti-tumor immunity and undermine the efficacy of anti-PD-1 therapy. However, the impact of anti-PD-1 treatment on these immunosuppressive cells has not been clearly defi...

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Bibliographic Details
Main Authors: Jiuxing Feng, Shujing Chen, Shuangqi Li, Baitong Wu, Jiacheng Lu, Li Tan, Jiamin Li, Yuanlin Song, Guoming Shi, Yujiang Geno Shi, Jinjun Jiang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Translational Oncology
Subjects:
NSCLC
M-MDSCs
Anti-PD-1 therapy
Tregs
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303570

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http://www.sciencedirect.com/science/article/pii/S1936523320303570

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