Selective Blockade of TNFR1 Improves Clinical Disease and Bronchoconstriction in Experimental RSV Infection

Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis in infants and young children. Although some clinical studies have speculated that tumor necrosis factor (TNF)-α is a major contributor of RSV-mediated airway disease, experimental evidence remains unclear or conflicting. TNF-α...

Full description

Bibliographic Details
Main Authors: Dorothea R. Morris, Maria Ansar, Teodora Ivanciuc, Yue Qu, Antonella Casola, Roberto P. Garofalo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
TNF
RSV
Online Access:https://www.mdpi.com/1999-4915/12/10/1176