Diagnostic and Prognostic Value of <i>B4GALT1</i> Hypermethylation and Its Clinical Significance as a Novel Circulating Cell-Free DNA Biomarker in Colorectal Cancer

Diagnostic and Prognostic Value of <i>B4GALT1</i> Hypermethylation and Its Clinical Significance as a Novel Circulating Cell-Free DNA Biomarker in Colorectal Cancer

Epigenetic modifications of glyco-genes have been documented in different types of cancer and are tightly linked to proliferation, invasiveness, metastasis, and drug resistance. This study aims to investigate the diagnostic, prognostic, and therapy-response predictive value of the glyco-gene <i&g...

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Main Authors: Francesco Picardo, Antonella Romanelli, Laura Muinelo-Romay, Tommaso Mazza, Caterina Fusilli, Paola Parrella, Jorge Barbazán, Rafael Lopez-López, Raffaela Barbano, Mariangela De Robertis, Chiara Taffon, Veronica Bordoni, Chiara Agrati, Manuela Costantini, Francesca Ricci, Paolo Graziano, Evaristo Maiello, Lucia Anna Muscarella, Vito Michele Fazio, Maria Luana Poeta
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
<i>b4galt1</i>
colorectal cancer
predictive biomarker
cetuximab
liquid biopsy
cfdna
Online Access:https://www.mdpi.com/2072-6694/11/10/1598

Internet

https://www.mdpi.com/2072-6694/11/10/1598

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