2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver.

Alternative splicing is a co-transcriptional mechanism that generates protein diversity by including or excluding exons in different combinations, thereby expanding the diversity of protein isoforms of a single gene. Abnormalities in this process can result in deleterious effects to human health, an...

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Bibliographic Details
Main Authors: Ana B Villaseñor-Altamirano, John D Watson, Stephenie D Prokopec, Cindy Q Yao, Paul C Boutros, Raimo Pohjanvirta, Jesús Valdés-Flores, Guillermo Elizondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219747