Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes

<p>Abstract</p> <p>Background</p> <p>The greatest challenges in vaccine development include optimization of DNA vaccines for use in humans, creation of effective single-dose vaccines, development of delivery systems that do not involve live viruses, and the identificati...

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Bibliographic Details
Main Authors: Silva Célio L, Faccioli Lúcia H, Ramos Simone G, Soares Édson G, Masson Ana P, Brandão Izaíra T, Souza Patrícia RM, Fonseca Denise M, Zárate-Bladés Carlos R, Trombone Ana PF, Frantz Fabiani G, Torre Lucimara, Rosada Rogério S, Santana Maria HA, Coelho-Castelo Arlete AM
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/38