Design, synthesis, and biological evaluation of novel bromo-pyrimidine analogues as tyrosine kinase inhibitors
In the present investigation we designed, synthesized and evaluated a novel series of bromo-pyrimidine analogues (6a-j, 7a-e, 9a-f, and 10a-f) as anticancer agents. The compounds were characterized using spectroscopic studies and elemental analysis and screened for their in vitro cytotoxic activity...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
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Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535221000691 |