Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cellsResearch in context

Background: Bone metastases are common and devastating to cancer patients. Existing treatments do not specifically target the disease sites and are therefore ineffective and systemically toxic. Here we present a new strategy to treat bone metastasis by targeting both the cancer cells (“the seed”), a...

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Bibliographic Details
Main Authors: Aude I. Segaliny, Jason L. Cheng, Henry P. Farhoodi, Michael Toledano, Chih Chun Yu, Beatrice Tierra, Leanne Hildebrand, Linan Liu, Michael J. Liao, Jaedu Cho, Dongxu Liu, Lizhi Sun, Gultekin Gulsen, Min-Ying Su, Robert L. Sah, Weian Zhao
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304281